a 110 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1813L	Dynorphin A 1-10 acetate(79994-24-4 free base)		Opioid Receptor
	Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.		Opioid Receptor
T26463	A110	A-110,A 110
	A110 is a potent and selective IMPDHs inhibitor. It binds to the NAD(+) cofactor site and forms a ternary complex with IMP.
TP1813	Dynorphin A (1-10)	Dynorphin A 1-10
	Dynorphin A (1-10), an endogenous opioid neuropeptide, interacts with the κ-opioid receptor by binding to its extracellular loop 2 and inhibits NMDA-activated current, demonstrating an IC50 value of 42.0 μM.
TP1423	Dynorphin A (1-10) TFA(79994-24-4,free)	Dynorphin A (1-10) TFA
	Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds in the transmembrane domain of the κ-receptor.
T6077	ZM-447439		Apoptosis , MEK , Src , Aurora Kinase
	ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect aga...		Apoptosis , MEK , Src , Aurora Kinase
T15830	M-110		Pim
	M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate ca...		Pim
T16742	Rhodamine 110	Rhodamine 110 chloride,RH110	Others
	Rhodamine 110 (RH110) is a xanthene dye similar to fluorescein and eosin.		Others
T7276	SD 0006	SD-06	p38 MAPK , Autophagy
	SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.		p38 MAPK , Autophagy
T22840	HexylHIBO		GluR
	HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.		GluR
T22263	Bavdegalutamide	ARV-110	Androgen Receptor
	Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati...		Androgen Receptor
T21587	Muraglitazar	Pargluva,BMS-298585	PPAR
	Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα and PPARγ with EC50 of 320 nM and 110 nM r...		PPAR
T6938	PF-4989216	PF 4989216	Apoptosis , PI3K
	PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.		Apoptosis , PI3K
T21915	TBCA	Casein Kinase II Inhibitor III, TBCA	Casein Kinase
	TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.		Casein Kinase
T10586L	BPH-1358	NSC50460	Others , Antibacterial
	BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. a...		Others , Antibacterial
T6445	Cilomilast	SB-207499,Ariflo	PDE
	Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.		PDE
T0957	Isradipine	PN 200-110	Calcium Channel , Autophagy
	Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc...		Calcium Channel , Autophagy
T6988	SKF 38393 hydrochloride	(±)-SKF-38393 hydrochloride,SKF-38393A,SKF38393 HCl	Dopamine Receptor
	SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist.		Dopamine Receptor
T2124	PJ34 hydrochloride	PJ34 HCl	PARP
	PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.		PARP
T14835	BTRX-335140	CYM-53093	Opioid Receptor
	BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140...		Opioid Receptor
T2500	Cediranib	AZD2171,NSC-732208	VEGFR , FLT , PDGFR , c-Kit , Autophagy
	Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...		VEGFR , FLT , PDGFR , c-Kit , Autophagy